Analysis of Antimicrobial Susceptibility in Bacterial Pathogens Associated with Urinary Tract Infections from Beijing Teaching Hospital in China, 2009–2017

Objective. Since a urinary tract infection (UTI) is easy to relapse and difficult treat, the antibiotic resistance rate has increased year by in recent years. This study was analyze characteristics of common pathogenic bacteria changes system infection, so as guide standard use antibiotics clinical control nosocomial effectively. Methods. A total 5,669 strains hospital from January 2009 December 2017 were retrospectively analyzed. Bacterial identification sensitivity test (AST) analyzed using VITEK-2 Compact system. Results. Of 5669 pathogens, 3,256 (57.44%) Gram-negative (GNB), 1,474 (26%) Gram-positive (GPB), 939 (16.56%) fungi. Resistant rates ESBL-producing all significantly different non-ESBL-producing Escherichia coli ( p < 0.05 ). The β-lactam higher than that Klebsiella pneumoniae id="M2"> detection vancomycin-resistantEnterococcus faecium Enterococcus faecalis 37.3% 3.1%, respectively, linezolid-resistantEnterococcus 0.68% 0%, respectively. drug candida sp. fluconazole, itraconazole, voriconazole 1.7%, 8.5%, 3.4%, No amphotericin B-resistant detected research. Conclusions. Among isolated patients, GNB main pathogens. major pathogen. ESBLs-producingEscherichia non-ESBLs-producingEscherichia general; meanwhile, β-lactam/β-lactamase inhibitors carbapenems maintained good antimicrobial activity against coli. non-ESBLs-producingKlebsiella ESBLs-producingKlebsiella strains, more prominent; most over 50%. faecalis. There rare linezolid-resistant strains. imidazole fungi controlled less 10%.